Czech Mycology 47(2): 145–150             Article published: 15th March, 1994 doi: 10.33585/cmy.47203


Potentiated effect of ethanol on Amanita phalloides poisoning.

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Interaction of the effects of death cap and ethanol in rats was studied. Ethanol was found to have no protective effect during poisoning by Amanita phalloides. In contrast, it burdened hepatocytes with its own detoxification and made the absorption of the fungal toxins easier due to a changed membrane fluidity. Besides, ethanol was responsible for an increased deimage to the cellular membranes by free radicals that originated in its metabolism. The potentiated effects of the two noxae is thus defined. Our results suggest that the intoxication by A. phalloides parallelled by digestion of a small dose of an alcoholic drink will have a more serious course and worse prognosis.

Keywords:     Amanita phalloides, ethanol, poisoning

Full citation:

Klán J., Zima T., Baudišová D. (1994): Potentiated effect of ethanol on Amanita phalloides poisoning. – Czech Mycology 47(2): 145–150. copy to clipboard

doi: 10.33585/cmy.47203

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