Aucubin, an iridoid glucoside, exhibits significant protective activities against Amanita poisoningin beagledogs. The post-injection of aucubin helps beaglessurvivefrom lethalpoisoning caused byAmanita virosa. Protective activities of aucubin resultfrom primarily preventing hepatic injury caused by Amanita poisoning, and is partly due to a protective affect of aucubin on the depression of m-RNA biosynthesis in the liver caused by a-amanitin intoxication.
Yamaura Y., Chang I. -M. (1995): Protective action against Amanita poisoning by iridoid glucoside, aucubin. – Czech Mycology 48(1): 67–72.